This guide contains information about places where you can stop for the night when driving from Sioux Falls, South Dakota to Myrtle Beach, South Carolina. Total distance for the trip is around 1503 miles with a driving time of approximately 22 hours 1 min. Cities and towns with hotels that are on the fastest route between Sioux Falls and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

86.8 miles from Sioux Falls (1 hour 18 mins)
1418 miles from Myrtle Beach (20 hours 51 mins)
185 miles from Sioux Falls (2 hours 44 mins)
1328 miles from Myrtle Beach (19 hours 35 mins)
362 miles from Sioux Falls (5 hours 14 mins)
1141 miles from Myrtle Beach (16 hours 51 mins)
491 miles from Sioux Falls (7 hours 1 min)
1018 miles from Myrtle Beach (15 hours 8 mins)
613 miles from Sioux Falls (8 hours 48 mins)
895 miles from Myrtle Beach (13 hours 19 mins)
785 miles from Sioux Falls (11 hours 25 mins)
723 miles from Myrtle Beach (10 hours 52 mins)
919 miles from Sioux Falls (13 hours 14 mins)
590 miles from Myrtle Beach (8 hours 57 mins)
1097 miles from Sioux Falls (15 hours 46 mins)
411 miles from Myrtle Beach (6 hours 22 mins)
1211 miles from Sioux Falls (17 hours 32 mins)
305 miles from Myrtle Beach (4 hours 43 mins)
1270 miles from Sioux Falls (18 hours 27 mins)
241 miles from Myrtle Beach (3 hours 50 mins)
1358 miles from Sioux Falls (19 hours 39 mins)
153 miles from Myrtle Beach (2 hours 33 mins)
1437 miles from Sioux Falls (20 hours 47 mins)
67.3 miles from Myrtle Beach (1 hour 19 mins)

Popular Hotels In Myrtle Beach

Book Hotels Online
or call 1-866-226-8756
Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.